Protective efficacy of active compounds from   P hyllanthus amarus  against white spot syndrome virus in freshwater crab (  P aratelphusa hydrodomous ) | Zendy

Sundaram Dinesh | Zendy; Kesavan Karthikeyan | Zendy; Kumaravel Hemalatha | Zendy; Mohammed Roohi Fatima | Zendy; Tohru Mekata | Zendy; Toshiaki Itami | Zendy; Raja Sudhakaran | Zendy

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Protective efficacy of active compounds from P hyllanthus amarus against white spot syndrome virus in freshwater crab ( P aratelphusa hydrodomous )

Author(s) -

Sundaram Dinesh,

Kesavan Karthikeyan,

Kumaravel Hemalatha,

Mohammed Roohi Fatima,

Tohru Mekata,

Toshiaki Itami,

Raja Sudhakaran

Publication year - 2016

Publication title -

aquaculture research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.646

H-Index - 89

eISSN - 1365-2109

pISSN - 1355-557X

DOI - 10.1111/are.12660

Subject(s) - white spot syndrome , biology , shrimp , bioassay , petroleum ether , traditional medicine , virus , virology , veterinary medicine , fishery , chromatography , ecology , medicine , chemistry , extraction (chemistry)

Repeatedly the shrimp culturing industry faces serious economic loss due to white spot disease caused by white spot syndrome virus ( WSSV ) in penaeid shrimp. The present study was carried out to determine the antiviral activity of traditional I ndian medicinal herb P hyllanthus amarus against WSSV in freshwater crab, P aratelphusa hydrodomous ( H erbst). For experimental challenge, crabs were injected with three different solvent extracts of P . amarus (aqueous, acetone and petroleum ether) along with WSSV . The efficacy of the extracts was confirmed by bioassay, histopathology and reverse transcriptase – polymerase chain reaction ( RT ‐ PCR ). The overall results of the present study confirmed that acetone and petroleum ether extracts of P . amarus have significant antiviral effect against WSSV .

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