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Trends in paediatric inflammatory bowel disease‐attributable direct costs: a population‐based analysis
Author(s) -
ElMatary Wael,
Nugent Zoann,
Witt Julia,
Bernstein Charles N.
Publication year - 2021
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/apt.16358
Subject(s) - medicine , inflammatory bowel disease , indirect costs , population , disease burden , health care , crohn's disease , pediatrics , resource use , disease , emergency medicine , demography , environmental health , accounting , natural resource economics , sociology , economics , business , economic growth
Summary Background In addition to its morbidities, inflammatory bowel disease (IBD) has a major financial burden on patients and healthcare systems. However, there is a paucity of evidence on IBD‐attributable costs in children. Aims To determine the trends of IBD‐attributable direct costs over time using a population‐based analysis. Methods Data were extracted from Manitoba Health Provider Claims and other population registry datasets from 1995 to 2017. Children with IBD were matched by age, sex and location with children without IBD. IBD‐attributable direct costs were calculated using utilization counts from the administrative data and cost estimates from different sources. Inpatient hospitalisation and outpatient procedure costs were estimated using the resource intensity weight (RIW) that is attached to each record in the data. Costs were expressed in Canadian dollars. Results We included 733 (428 with Crohn's disease) prevalent cases who were diagnosed with IBD before the age of 18 years and were followed for 2450 person‐years. A matched control group of 6763 persons who were followed for 21 558 person‐years was included. The median annual costs of physician services billed per patient increased from $381 (IQR 215‐1064) in 1995 to $936 (IQR 579‐1932) in 2017 ( P < 0.001). The annual medication costs per patient increased from a median of $270 in 1995 to $7944 in 2017 ( P < 0.0001). The median annual direct cost per patient was $1810 in 2004 as compared to $14 791 ( P < 0.0001) in 2017. Conclusions Over two decades, there was a significant increase in the paediatric IBD‐attributable direct costs mainly driven by medication costs.