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Determinants of IBD‐related disability: a cross‐sectional survey from the GETAID
Author(s) -
Tannoury Jenny,
Nachury Maria,
Martins Carole,
Serrero Melanie,
Filippi Jerome,
Roblin Xavier,
Bourrier Anne,
Bouguen Guillaume,
Franchimont Denis,
Savoye Guillaume,
Buisson Anthony,
Louis Edouard,
Nancey Stephane,
Abitbol Vered,
Reimund JeanMarie,
DeWitt Olivier,
Vuitton Lucine,
Mathieu Nicolas,
PeyrinBiroulet Laurent,
Gilletta Cyrielle,
Allez Matthieu,
Viennot Stephanie,
TrangPoisson Caroline,
Laharie David,
Amiot Aurelien
Publication year - 2021
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/apt.16353
Subject(s) - medicine , ulcerative colitis , cross sectional study , inflammatory bowel disease , population , disease , physical therapy , pathology , environmental health
Summary Background The burden of inflammatory bowel disease (IBD) is rising worldwide. The goal of IBD treatment is to achieve clinical and endoscopic remission but also prevent disability. Aims To identify the predictive factors of disability in a large population of patients with IBD. Patients and methods We conducted a cross‐sectional survey in 42 tertiary centres in France and Belgium. A self‐administered questionnaire was designed to explore patients and their IBD characteristics. IBD‐disk is a validated tool to measure disability in patients with IBD. The IBD‐disk score was then calculated for each patient. Based on a previous study, an overall IBD‐disk score ≥40 was associated with moderate‐to‐severe disability. Results Among the 2011 patients, 1700 were analysed, including 746 (44%) in self‐reported clinical remission and 752 (44.2%) declaring clinical activity. The patient global assessment of global remission was missing in 200 (11.8%) of 1700 patients. Moderate‐to‐severe disability was significantly increased in patients with BMI >25 kg/m 2 (OR = 1.66; 95% CI [1.29‐2.14]), in those having perception of need for a psychotherapist (OR = 2.24; 95% CI [1.79‐3.05]) and social worker (OR = 1.54; 95% CI [1.08‐2.21]). Conversely, male gender (OR = 0.83; 95% CI [0.69‐0.99]), ulcerative colitis (OR = 0.69; 95% CI [0.53‐0.92]), self‐reported clinical remission (OR = 0.59; 95% CI [0.46‐0.77]) and employed or student occupational status (OR = 0.69; 95% CI [0.52‐0.92]) were inversely correlated with disability. Overall, 257 (34.5%) patients who declared being in clinical remission had disability. Conclusion Determinants of IBD‐related disability include IBD‐related factors but also psychological and social factors. This highlights the importance of a multidisciplinary team in the management of patients with IBD.