Increased risk of herpes zoster among 108 604 patients with inflammatory bowel disease | Zendy

Long M. D. | Zendy; Martin C. | Zendy; Sandler R. S. | Zendy; Kappelman M. D. | Zendy

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Increased risk of herpes zoster among 108 604 patients with inflammatory bowel disease

Author(s) -

Long M. D.,

Martin C.,

Sandler R. S.,

Kappelman M. D.

Publication year - 2013

Publication title -

alimentary pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.308

H-Index - 177

eISSN - 1365-2036

pISSN - 0269-2813

DOI - 10.1111/apt.12182

Subject(s) - medicine , inflammatory bowel disease , nested case control study , ulcerative colitis , cohort , retrospective cohort study , crohn's disease , cohort study , logistic regression , case control study , rate ratio , proportional hazards model , incidence (geometry) , risk factor , gastroenterology , disease , confidence interval , physics , optics

Summary Background Patients with inflammatory bowel disease ( IBD ) on certain immunosuppressants have increased herpes zoster ( HZ ) risk. Aim To determine the risk of HZ in IBD and how antitumour necrosis factor‐alpha (anti‐ TNF ) agents affect this risk. Methods We performed a retrospective cohort and nested case–control study using administrative data from IMS LifeLink ® Information Assets‐Health Plan Claims Database. In the cohort, we identified IBD patients

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