Premium
NICE clinical guideline (CG152): the management of Crohn's disease in adults, children and young people
Author(s) -
Mayberry J. F.,
Lobo A.,
Ford A. C.,
Thomas A.
Publication year - 2013
Publication title -
alimentary pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.308
H-Index - 177
eISSN - 1365-2036
pISSN - 0269-2813
DOI - 10.1111/apt.12102
Subject(s) - nice , guideline , medicine , excellence , evidence based medicine , critical appraisal , evidence based practice , crohn's disease , disease , medline , family medicine , best practice , cost effectiveness , intensive care medicine , alternative medicine , pathology , risk analysis (engineering) , management , computer science , political science , law , economics , programming language
Background The guideline offers best practice advice on the care of adults, children and young people with Crohn's disease. Aim To provide clinically effective and cost‐effective evidence‐based recommendations to guide clinical practice in a clinical guideline commissioned by the National Institute for Health and Clinical Excellence (NICE). Methods A systematic review of the evidence including critical appraisal, meta‐analysis and cost‐effectiveness modelling. Results Thirty‐one evidence‐based recommendations covering induction and maintenance therapy are available. Five key priorities for implementation are identified together with nine future research recommendations. Three guideline versions are available: short (containing just the recommendations), full (containing the full evidence base) and an Understanding NICE guidance for patients and carers. Algorithms have been produced together with a NICE pathway and implementation tools. Conclusion These are the first evidence‐based clinical and cost‐effectiveness guidelines for Crohn's disease in the United Kingdom.