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Autoantibodies in autoimmune liver diseases
Author(s) -
Sener Asli Gamze
Publication year - 2015
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/apm.12442
Subject(s) - autoantibody , autoimmune hepatitis , primary biliary cirrhosis , medicine , immunology , hepatitis , primary sclerosing cholangitis , etiology , gamma globulin , cirrhosis , antibody , pathology , disease , gastroenterology
Autoimmune hepatitis is a chronic hepatitis of unknown etiology characterized by clinical, histological, and immunological features, generally including circulating autoantibodies and a high total serum and/or gamma globulin. Liver‐related autoantibodies are very significant for the correct diagnosis and classification of autoimmune liver diseases (AILD), namely autoimmune hepatitis types 1 and 2 (AIH‐1 and 2), primary biliary cirrhosis (PBC), and the sclerosing cholangitis types in adults and children. This article intends to review recent studies that investigate autoantibodies in autoimmune liver diseases from a microbiological perspective.