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In vitro antimicrobial profile of U reaplasma urealyticum from genital tract of childbearing‐aged women in N orthern and S outhern I taly
Author(s) -
Pignanelli Salvatore,
Pulcrano Giovanna,
Iula Vita Dora,
Zaccherini Patrizia,
Testa Antonio,
Catania Maria Rosaria
Publication year - 2014
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1111/apm.12184
Subject(s) - antimicrobial , microbiology and biotechnology , antibiotics , ureaplasma urealyticum , pathogen , medicine , biology , mycoplasma
U reaplasma urealyticum is an opportunistic pathogen during pregnancy and in newborns. Other clinical problems related to U . urealyticum infections are: no susceptibility to cell wall‐active drugs, limits of antibiotic treatment in pregnancy, and spread of antimicrobial resistance. In addition, the results of antimicrobial susceptibility against U . urealyticum from various countries are few and controversial. The antimicrobial susceptibility of U . urealyticum , isolated from cervical swabs and collected from outpatient childbearing‐aged women in I taly from 2009 to 2012, was performed against fluoroquinolones, macrolides, streptogramin and tetracyclines, using an available biochemical commercial kit and a specific solid culture medium, to improve the therapeutic management of these pathogenic agents. U reaplasma urealyticum was detected in 49.4% of samples, but significant bacterial load was revealed in 29.8%. In vitro tetracyclines showed the best activity against U . urealyticum , followed by streptogramin, macrolides, and fluoroquinolones.