Premium
Gene expression and delayed nephrogenesis in the growth‐restricted rat foetus and neonate
Author(s) -
Carter A. M.
Publication year - 2018
Publication title -
acta physiologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.591
H-Index - 116
eISSN - 1748-1716
pISSN - 1748-1708
DOI - 10.1111/apha.13000
Subject(s) - biology , nephron , intrauterine growth restriction , offspring , medicine , fetus , endocrinology , kidney development , pregnancy , physiology , andrology , kidney , gene , embryonic stem cell , genetics
In this issue of Acta Physiologica, Cuffe et al. [1] explore the molecular mechanisms behind impaired nephrogenesis in a rat model of uteroplacental insufficiency and fetal growth restriction. Nephron development was delayed after growth restriction, continuing late into the postnatal period, and this was reflected in increased abundance of branching morphogenesis genes a week after birth. This article is protected by copyright. All rights reserved.