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The exocytotic machinery
Author(s) -
Eliasson L.
Publication year - 2014
Publication title -
acta physiologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.591
H-Index - 116
eISSN - 1748-1716
pISSN - 1748-1708
DOI - 10.1111/apha.12235
Subject(s) - exocytosis , secretion , microbiology and biotechnology , vesicle , neurotransmitter , munc 18 , intracellular , secretory vesicle , vesicle fusion , golgi apparatus , extracellular vesicle , extracellular , synaptic vesicle , biology , chemistry , neuroscience , gene , biochemistry , microvesicles , membrane , endoplasmic reticulum , microrna , central nervous system
Exocytosis is the mechanism by which a vesicle inside the cell fuses with the plasma membrane to release its contents into the extracellular environment. The process might sound trivial but reduced expression or mutations in genes involved can cause a variety of disease states. The exocytotic process is a necessary part of neurotransmitter release from the pre-synaptic side into the synaptic cleft as well as for secretion of hormones from neuroendocrine and endocrine cells. This article is protected by copyright. All rights reserved