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Birthweight z‐score and fat‐free mass at birth predict body composition at 3 years in Danish children born from obese mothers
Author(s) -
Berglund Nanna R.,
Lewis Jack I.,
Michaelsen Kim F.,
Mølgaard Christian,
Renault Kristina M.,
Carlsen Emma M.
Publication year - 2022
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.16346
Subject(s) - bioelectrical impedance analysis , medicine , anthropometry , fat free mass , fat mass , body mass index , danish , mass index , demography , body adiposity index , cohort , cohort study , dual energy x ray absorptiometry , pediatrics , composition (language) , classification of obesity , bone mineral , osteoporosis , sociology , linguistics , philosophy
Abstract Aim We investigated associations between newborn body composition and anthropometry and body composition at 3 years in Danish children born from obese mothers. Methods Analyses are based on data from the observational cohort study SKOT II (SKOT; small children's diet and well‐being (Danish)). Body composition at birth and at 3 years was assessed by dual‐energy X‐ray absorptiometry (DXA) scans and bioelectrical impedance analysis (BIA), respectively. Multiple linear regression models were applied to determine associations between newborn body composition and anthropometry and body composition at 3 years. Results Birthweight z‐score (BWZ) was positively associated with fat‐free mass (FFM), height, fat‐free mass index (FFMI), fat mass (FM) and fat mass index (FMI) at 3 years. Newborn FFM was positively associated with FFM, height, FFMI and FM at 3 years, and positive trends were seen between newborn FM and FM and FMI at 3 years. Conclusion We showed that infants born with a higher BWZ go on to be taller at 3 years. They also grow to be heavier, to which FM and FFM both contribute, independently of linear growth. Additionally, it seems that FFM tracks into early childhood, thus supporting intrauterine programming of later health.