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Neurodevelopmental disorders and somatic diagnoses in a national cohort of children born before 24 weeks of gestation
Author(s) -
Morsing Eva,
Lundgren Pia,
Hård AnnaLena,
Rakow Alexander,
HellströmWestas Lena,
Jacobson Lena,
Johnson Mats,
Nilsson Staffan,
Smith Lois E.H.,
Sävman Karin,
Hellström Ann
Publication year - 2022
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.16316
Subject(s) - medicine , gestation , cohort , pediatrics , somatic cell , cohort study , obstetrics , pregnancy , genetics , gene , biology
Aim This study investigated childhood diagnoses in children born extremely preterm before 24 weeks of gestation. Methods Diagnoses of neurodevelopmental disorders and selected somatic diagnoses were retrospectively retrieved from national Swedish registries for children born before 24 weeks from 2007 to 2018. Their individual medical files were also examined. Results We studied 383 children born at a median of 23.3 (range 21.9–23.9) weeks, with a median birthweight of 565 (range 340–874) grams. Three‐quarters (75%) had neurodevelopmental disorders, including speech disorders (52%), intellectual disabilities (40%), attention deficit hyperactivity disorder (30%), autism spectrum disorders (24%), visual impairment (22%), cerebral palsy (17%), epilepsy (10%) and hearing impairment (5%). More boys than girls born at 23 weeks had intellectual disabilities (45% vs. 27%, p < 0.01) and visual impairment (25% vs. 14%, p < 0.01). Just over half of the cohort (55%) received habilitation care. The majority (88%) had somatic diagnoses, including asthma (63%) and failure to thrive/short stature (39%). Conclusion Most children born before 24 weeks had neurodevelopmental disorders and/or additional somatic diagnoses in childhood and were referred to habilitation services. Clinicians should be aware of the multiple health and developmental problems affecting these children. Resources are needed to identify their long‐term support needs at an early stage.