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Neurodevelopmental problems in children with febrile seizures followed to young school age: A prospective longitudinal community‐based study in Sweden
Author(s) -
Nilsson Gill,
Lundström Sebastian,
Fernell Elisabeth,
Gillberg Christopher
Publication year - 2022
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.16171
Subject(s) - medicine , pediatrics , cohort , neurodevelopmental disorder , autism , tics , prospective cohort study , longitudinal study , cohort study , psychiatry , surgery , pathology
Aim To estimate the accumulated prevalence of neurodevelopmental problems from preschool to school age in children with a history of febrile seizures (FS). Methods In a community‐based cohort of children with previous FS, 25/73 clinically assessed children met diagnostic criteria for neurodevelopmental disorders or had major indications of such problems at the age of 4–5 years. Parents of 54 of the 73 children accepted to take part in an interview according to the Autism‐Tics, ADHD and other Comorbidities (A‐TAC) inventory, when the children were 9–10 years. Results There was a trend for ADHD symptom scores to be higher in the FS group. Non‐participants at age 9–10 years had had much higher rates of neurodevelopmental problems at 4–5 years, and the total number of such problems at either 4–5 or age 9–10 was 41% (30/73). Conclusion High rates of neurodevelopmental problems (41%) were found at either age 4–5 or 9–10 years or both in this group of 7 3 children with FS. Non‐participants at 9–10 years had had much higher rates of neurodevelopmental problems at 4–5 years. Further follow‐up of this cohort is needed before definite conclusions can be drawn about whether FS should be considered a marker for more complex neurodevelopmental problems.