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Definitive pathognomonic signs and symptoms of paediatric neurological COVID‐19 are still emerging
Author(s) -
Verrotti Alberto,
Mazzocchetti Chiara,
Iannetti Paola
Publication year - 2021
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.15827
Subject(s) - medicine , pathognomonic , covid-19 , disease , pandemic , kawasaki disease , pediatrics , multisystem disease , intensive care medicine , pathology , infectious disease (medical specialty) , outbreak , artery
Children with COVID‐19 tend to show milder symptoms than adults during the pandemic, but growing evidence of neurological involvement has emerged. Some studies have reported neurological symptoms in children with COVID‐19, which include multisystem inflammatory syndrome, a disease that shares some, but not all, of the characteristics of Kawasaki disease. This review presents, and discusses, the evidence to date. Our initial findings suggest that neurological manifestations can be considered to be the direct result of central nervous system viral invasion or post‐infection immuno‐mediated disease.