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Maternal pre‐pregnancy underweight as a risk factor for the offspring: Survey of Neonates in Pomerania
Author(s) -
Domanski Grzegorz,
Lange Anja Erika,
Ittermann Till,
Fallenberg Jonas,
Allenberg Heike,
Zygmunt Marek,
Heckmann Matthias
Publication year - 2021
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.15701
Subject(s) - underweight , medicine , pregnancy , offspring , obstetrics , population , overweight , cohort study , birth weight , pediatrics , demography , body mass index , environmental health , genetics , sociology , biology
Aim The aim was to investigate socio‐economic risk factors for maternal underweight before pregnancy and then associations of underweight with neonatal outcomes. Methods Data of 3401 mother‐child dyads from the population‐based birth cohort Survey of Neonates in Pomerania (SNiP) were analysed. Results Bivariate analysis showed that underweighted mothers were younger, smoked more often, had a lower equivalent income and lower socio‐economic status (employment status and/or educational level) compared to women with normal weight. The final prediction model revealed that only younger maternal age (OR = 0.93; 95%‐CI = 0.90‐0.97) and maternal smoking during pregnancy (OR = 2.52; 95%‐CI = 1.74‐3.66) were associated with underweight. Compared to women with normal pre‐pregnancy BMI, underweight women had an increased chance of premature labour (OR = 1.73; 95% CI: 1.29‐2.31) and a reduced placental weight. The offspring of underweight women had an increased risk of late preterm birth (OR = 1.82; 95% CI: 1.21‐2.74) and birthweight < 2500 g (OR = 1.91; 95% CI: 1.23‐2.95). Conclusion Smoking during pregnancy and a younger age were identified as risk factors for maternal pre‐pregnancy underweight which then was associated with late preterm birth and low birthweight.