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Infant neurobehavioural consequences of prenatal cigarette exposure: A systematic review and meta‐analysis
Author(s) -
Froggatt Suzanne,
Covey Judith,
Reissland Nadja
Publication year - 2020
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.15132
Subject(s) - irritability , lethargy , medicine , cinahl , psycinfo , meta analysis , pregnancy , prenatal stress , medline , clinical psychology , anxiety , psychiatry , offspring , psychological intervention , biology , political science , law , genetics
Aim Prenatal exposure to cigarettes leads to alterations in brain development during pregnancy. This has an impact on postnatal psychological and behavioural processes, affecting an infant's neurobehavioural profile with little known about which aspects are affected. The evidence was synthesised to assess the effects of prenatal cigarette smoke exposure on neurobehavioural outcomes within the first year of life. Methods Six databases were searched (Web of Science Core Collections, MEDLINE, PsycINFO, CINAHL, EBSCOhost eBook Collection and OpenGrey) in November 2018. Eligible studies (n = 17) had to include a measure of prenatal cigarette exposure and a neurobehavioural assessment ≤1 year of age. Results In the first year of life, specific areas of neurobehavioural functioning are related to prenatal cigarette exposure with eight out of 10 areas of neurobehaviour having significant medium (negative affect, attention, excitability, irritability and orientation) or small (muscle tone, regulation and difficult temperament) pooled effect sizes. Only lethargy and stress did not show any significant pooled effects. Conclusion Prenatal cigarette exposure affects a significant range of behaviours during the first year of life.