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An overview of how on‐call consultant paediatricians can recognise and manage severe primary immunodeficiencies
Author(s) -
Wekell Per,
Hertting Olof,
Holmgren Daniel,
Fasth Anders
Publication year - 2019
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.14930
Subject(s) - medicine , primary immunodeficiency , pediatrics , severe combined immunodeficiency , primary care , disease , intensive care medicine , family medicine , pathology , biochemistry , chemistry , gene
Severe primary paediatric immunodeficiency syndromes are rare and potentially fatal unless suspected, diagnosed and treated early. We provide clinical guidance and support for on‐call consultant paediatricians working in secondary level hospitals on how to recognise and manage children with these conditions. Our paper addresses four conditions that risk the most severe outcomes if they are not adequately cared for during on‐call periods, such as weekends: severe combined immunodeficiency, haemophagocytic lymphohistiocytosis, severe congenital neutropaenia and chronic granulomatous disease. Conclusion On‐call paediatricians are provided with advice on handling the most severe primary immunodeficiencies.