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Factors contributing to the failure of humidified high‐flow nasal cannulae
Author(s) -
Teoh Sophia,
Clyde Elizabeth,
Dassios Theodore,
Greenough Anne
Publication year - 2018
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.14415
Subject(s) - medicine , flow (mathematics) , intensive care medicine , mechanics , physics
The use of humidified high-flow nasal cannulae (HHFNC) as an alternative mode of non-invasive ventilation (NIV) in neonates has become widespread. A survey of UK neonatal units showed the proportion using HHFNC had increased from 56% in 2012 to 87% in 2015 (1). A recently reported Cochrane Review (2) comparing the use of HHFNC against other NIV modes of ventilation immediately after birth or following extubation showed no significant difference in the rates of bronchopulmonary dysplasia (BPD) or death and no significant difference in the rates of treatment failure/reintubation. Benefits cited include a significantly reduced risk of nasal trauma as compared to continuous positive airway pressure (CPAP). Furthermore, both medical staff and parents (3) were found to prefer HHFNC to CPAP. Identification of infants in whom use of HHFNC as either a primary or step-down mode of respiratory support may be inappropriate might further reduce the failure rate of HHFNC. This article is protected by copyright. All rights reserved.

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