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Assessing truncal obesity in predicting cardiometabolic risk in children: clinical measures versus dual‐energy X‐ray absorptiometry
Author(s) -
Palmieri Vincent J.,
Henshaw Melissa H.,
Carter Janet,
Chowdhury Shahryar M.
Publication year - 2018
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.14175
Subject(s) - medicine , waist to height ratio , insulin resistance , obesity , waist–hip ratio , waist , dyslipidemia , trunk , dual energy x ray absorptiometry , endocrinology , bone mineral , ecology , osteoporosis , biology
Aim The objectives of this study were to 1) compare the accuracy of waist:hip ratio (WHR) and waist:height ratio (WHtR) by determining their association with reference‐standard measures derived from dual‐energy X‐ray absorptiometry (DXA) and 2) assess the relationship of DXA, WHR and WHtR to measures of dyslipidemia, insulin resistance and inflammation in children. Methods Subjects aged four to 21 were prospectively recruited. Truncal obesity by DXA was defined as the trunk fat:height ratio and trunk fat:nontrunk fat ratio. Three hundred and eight subjects were studied, and 246 (80%) were obese. Results There was a strong correlation between WHtR and trunk fat:height (r = 0.84, p < 0.01). DXA measures of truncal obesity had stronger correlations with measures of cardiometabolic risk than WHR and WHtR. Upon multivariable regression, only WHtR had independent associations with cholesterol/HDL, HOMA‐IR and high‐sensitivity c‐reactive protein. Conclusion WHtR is an accurate measure of truncal obesity. WHtR showed stronger associations with measures of insulin resistance and truncal obesity than WHR.