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Phototherapy is commonly used for neonatal jaundice but greater control is needed to avoid toxicity in the most vulnerable infants
Author(s) -
Mreihil Khalaf,
Benth Jūratė Šaltytė,
Stensvold Hans Jørgen,
Nakstad Britt,
Hansen Thor Willy Ruud
Publication year - 2018
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.14141
Subject(s) - medicine , discontinuation , pediatrics , jaundice , gestational age , norwegian , intensive care , population , pregnancy , intensive care medicine , surgery , environmental health , linguistics , philosophy , genetics , biology
Aim Limited information is available about how guidelines on phototherapy for neonatal jaundice are applied in practice and toxicity is a concern. We studied the use of phototherapy in relation to birthweight and gestational age ( GA ) in Norwegian neonatal intensive care units ( NICU s). Methods The study population was all 5382 infants admitted to the 21 NICU s in Norway between September 1, 2013 and August 31, 2014. Data were recorded daily in the Norwegian Neonatal Network database and anonymised data on patient characteristics, diagnoses, duration, the ages at the start and discontinuation of phototherapy were analysed. Results More than a quarter (26.6%) of all infants admitted to Norwegian NICU s during the study period received phototherapy. The use of phototherapy was inversely related to GA and birthweight. More than 80% of the preterm infants under 28 weeks of GA received phototherapy. The duration was significantly longer in the lowest birthweight and GA groups and decreased with increasing birthweight and GA . Conclusion Phototherapy is proved to be a strong candidate for the most common therapeutic modality in NICU infants. However, in the light of reported toxicity in the smallest, most vulnerable infants, we recommend increased emphasis on quality control.
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