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Neural breathing pattern in newborn infants pre‐ and postextubation
Author(s) -
Iyer Narayan P.,
Dickson John,
Ruiz Michelle E.,
Chatburn Robert,
Beck Jennifer,
Sinderby Chister,
Rodriguez Ricardo J.
Publication year - 2017
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.14040
Subject(s) - medicine , anesthesia , intubation , breathing , diaphragm (acoustics) , physics , acoustics , loudspeaker
Abstract Aim To describe the neural breathing pattern before and after extubation in newborn infants. Methods Prospective, observational study. In infants deemed ready for extubation, the diaphragm electrical activity ( EA di) was continuously recorded from 30 minute before to two hours after extubation. Results Total of 25 neonates underwent 29 extubations; 10 extubations resulted in re‐intubation within 72 hours. Postextubation, there was an increase in peak EA di ( EA di‐max) and EA di‐delta (peak minus minimum EA di) in both groups. The pre‐ to postextubation change in EA di‐max (8.9–11.1 μv) and EA di‐delta (6–8 μv) was less in the failure group in comparison with the change in EA di‐max (10.2–13.4 μv) and EA di‐delta (6.3–10.6 μv) in the success group, (p = 0.02 and 0.01, respectively). Conclusion In our neonatal cohort, extubation failure was associated with a smaller increase in peak and delta EA di after extubation. If confirmed, these findings indicate an important cause of extubation failure in preterm infants.

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