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Velocity vector imaging shows normal cardiac systolic function in survivors of severe bronchopulmonary dysplasia at six to 16 years of age
Author(s) -
Suursalmi Piia,
Ojala Tiina,
Poutanen Tuija,
Eerola Anneli,
Korhonen Päivi,
Kopeli Tarja,
Tammela Outi
Publication year - 2017
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.13860
Subject(s) - medicine , bronchopulmonary dysplasia , cardiology , cardiac function curve , gestational age , odds ratio , heart failure , pregnancy , genetics , biology
Aim This study evaluated global myocardial function and associations between cardiac function and lung function in very low birth weight ( VLBW ) children, with and without severe radiographic bronchopulmonary dysplasia ( BPD ), at six to 14 years of age. Methods We studied 34 VLBW and 19 term‐born controls, and the VLBW group was further divided into a BPD group with severe radiographic BPD and those without radiographic BPD in infancy. Detailed right and left ventricular myocardial functions were analysed by velocity vector imaging, and the left ventricular mass was calculated. The associations between cardiac function and lung function were assessed by impulse oscillometry. Results The right and left ventricular myocardial systolic functions and the left ventricular mass were similar in the three groups. Lung function was not associated with cardiac systolic function. Neonatal exposure to dexamethasone treatment was negatively associated with right ventricular function, as measured by the automated fractional area change, with an odds ratio of 7.9 and 95% confidence interval of 1.9–33.5 (p = 0.005). Conclusion Lung function measurements were not associated with cardiac systolic function in preterm infants at six to 14 years of age. Neonatal exposure to dexamethasone, used for weaning from the ventilator, was negatively associated with right ventricular function.