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Addressing the burden of neonatal hyperbilirubinaemia in countries with significant glucose‐6‐phosphate dehydrogenase deficiency
Author(s) -
Olusanya Bolajoko O.,
Emokpae Abieyuwa A.,
Zamora Tara G.,
Slusher Tina M.
Publication year - 2014
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.12735
Subject(s) - medicine , glucose 6 phosphate dehydrogenase deficiency , jaundice , pediatrics , glucose 6 phosphate dehydrogenase , glucosephosphate dehydrogenase deficiency , low and middle income countries , environmental health , intensive care medicine , developing country , dehydrogenase , biochemistry , chemistry , economics , enzyme , economic growth
Glucose‐6‐phosphate dehydrogenase (G6 PD ) deficiency is an established worldwide risk factor for severe hyperbilirubinaemia. This literature review examined the pattern and management of severe hyperbilirubinaemia in low‐ and middle‐income countries ( LMIC s) where G6 PD deficiency was 10% or more and found that it was frequently associated with neonatal mortality and, or, neurodevelopmental disorders. Conclusion Low‐ and middle‐income countries need to pay urgent attention to G6 PD deficiency to curtail the preventable burden of jaundice‐related morbidity, mortality and disability.