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Higher systolic blood pressure with normal vascular function measurements in preterm‐born children
Author(s) -
Edwards Martin O.,
Watkins William John,
Kotecha Sarah J.,
Halcox Julian P. J.,
Dunstan Frank D.,
Henderson Alexander John,
Kotecha Sailesh
Publication year - 2014
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.12699
Subject(s) - medicine , arterial stiffness , blood pressure , low birth weight , cohort , birth weight , cardiology , pediatrics , cohort study , pregnancy , biology , genetics
Preterm birth, low birth weight and poor foetal nutrition have been linked to cardiovascular disease, but the underlying mechanisms remain unclear. We explored prematurity and vascular function by studying a UK cohort of 14 049 children and conducting a systematic review. Conclusion Systolic blood pressure was higher in subjects born preterm than term, but there were no differences in endothelial dysfunction or arterial stiffness. The systematic review revealed no clear association between prematurity and vascular function.