Premium
Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia?
Author(s) -
Sola Augusto,
Golombek Sergio G.,
Montes Bueno María Teresa,
LemusVarela Lourdes,
Zuluaga Claudia,
Domínguez Fernando,
Baquero Hernando,
Young Sarmiento Alejandro E.,
Natta Diego,
Rodriguez Perez Jose M.,
Deulofeut Richard,
Quiroga Ana,
Flores Gabriel Lara,
Morgues Mónica,
Pérez Alfredo GarcíaAlix,
Van Overmeire Bart,
Bel Frank
Publication year - 2014
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.12692
Subject(s) - hyperoxia , medicine , hypoxia (environmental) , supplemental oxygen , oxygen saturation , intensive care medicine , safer , clinical trial , pediatrics , clinical practice , oxygen , anesthesia , nursing , chemistry , organic chemistry , lung , computer security , computer science
Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation ( S p O 2 ) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials. Conclusion S p O 2 of 85–89% can increase mortality and 91–95% can cause hyperoxia and ill effects. Neither of these ranges can be recommended, and wider intermediate targets, such as 87–94% or 88–94%, may be safer.