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Probiotics for childhood functional gastrointestinal disorders: a systematic review and meta‐analysis
Author(s) -
Korterink Judith J,
Ockeloen Lize,
Benninga Marc A,
Tabbers Merit M,
Hilbink Mirrian,
DeckersKocken Judith M
Publication year - 2014
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.12513
Subject(s) - medicine , irritable bowel syndrome , functional constipation , meta analysis , functional gastrointestinal disorder , constipation , probiotic , abdominal pain , placebo , systematic review , intensive care medicine , medline , physical therapy , alternative medicine , pathology , biology , bacteria , genetics , political science , law
A systematic review and meta‐analysis were performed to investigate the quantity and quality of the current evidence regarding the effect of different probiotic strains in the treatment of functional gastrointestinal disorders ( FGID ) in children and adolescents. Conclusion Probiotics are more effective than placebo in the treatment of patients with abdominal pain‐related FGID , especially with respect to patients with irritable bowel syndrome. To date, however, probiotics have not proved effective for children with functional constipation.