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Growth charts and long‐term sequelae in extreme preterm infants – from full‐term age to 10 years
Author(s) -
Horemuzova Eva,
Åmark Per,
Jacobson Lena,
Söder Olle,
Hagenäs Lars
Publication year - 2014
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.12451
Subject(s) - medicine , pediatrics , head circumference , birth weight , cohort , standard score , retrospective cohort study , demography , pregnancy , genetics , machine learning , sociology , computer science , biology
Aim To describe growth pattern from full‐term age to 10 years in infants born before 26 weeks of gestation. Method This retrospective longitudinal cohort contained 123 children from Karolinska Hospital, Stockholm, during 1990–2002. Length/height (Ht), weight (Wt) and head circumference ( HC ) were recorded monthly during the first year, every 3 months until 2 years and yearly thereafter, but HC at 15 months and at median age of 8.1/9.7 years (range 2–14) in boys/girls. Results For boys/girls at birth, the mean Z‐score for Ht was −0.2/−0.2, for Wt 0.0/−0.2 and for HC 0.0/−0.3. At term, the mean Z‐score for Ht was −3.8/−3.1, for Wt −3.0/−2.5 and for HC −1.7/−1.2. At 1 year, the mean Z‐score for Ht was−1.3/−1.3, for Wt −1.9/−1.7 and for HC −1.2/−1.0. At 2 years, the mean Z‐score for Ht was −1.3/−1.1, for Wt −1.6/−1.2 and at 10 years for Ht −0.7/−0.4; that was on average −0.3 below mid‐parental height; for Wt −0.2/−0.2. Long‐term sequelae were found in 48% of the boys and 34% of the girls. Conclusion By 10 years of age, the attained mean Ht was in accordance with their genetic potential and almost half of these children had significant long‐term sequelae.