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Somatic growth in 94 single ventricle children – comparing systemic right and left ventricle patients
Author(s) -
Hessel Trine Witzner,
Greisen Gorm,
Idorn Lars,
Reimers Jesper Irving
Publication year - 2013
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/apa.12032
Subject(s) - ventricle , medicine , fontan procedure , gestational age , cardiology , hypoplastic left heart syndrome , surgery , heart disease , pregnancy , biology , genetics
Aim We sought to compare and assess growth in single ventricle children with a systemic right or left ventricle in five time periods: at birth, before neonatal surgery, before the G lenn anastomosis and finally before and after the Fontan operation to 11 years of age. Methods We reviewed medical records on 116 single ventricle patients operated at Rigshospitalet, D enmark from 1987 to 2007. Surgical procedures, feeding route, hemodynamic variables and anthropometric measurements such as weight and height were registered and converted to z‐scores. Results Ninety four single ventricle patients were included for analysis. Gestational age and birth weight was not significantly different between the left and right ventricle group. Before neonatal surgery and before the G lenn anastomosis, both groups showed equal growth retardation. However, a significant difference in catch‐up growth was found before the F ontan operation. Thus, patients in the right ventricle group had a smaller median weight‐for‐age z‐score compared with the left ventricle group in the pre‐ F ontan period (−1.9 and −1.6; p = 0.049) and in the post‐ F ontan period (−1.1 and −0.7; p = 0.034). Conclusion After the G lenn anastomosis single ventricle children with a systemic left ventricle have better weight gain compared with children with a systemic right ventricle.