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Silicone oil in vitreoretinal surgery: indications, complications, new developments and alternative long‐term tamponade agents
Author(s) -
Chen Ying,
Kearns Victoria R,
Zhou Liangyu,
Sandinha Teresa,
Lam Wai Ching,
Steel David H,
Chan Yau Kei
Publication year - 2021
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.14604
Subject(s) - tamponade , medicine , vitreoretinal surgery , silicone , silicone oil , surgery , risk analysis (engineering) , vitrectomy , engineering , materials science , visual acuity , chemical engineering , composite material
Silicone oil (SO) has been used as a long‐term tamponade agent in the treatment of complicated vitreoretinal diseases for about half a century, during which time many advances in surgical techniques and technologies have been made. This review summarizes the chemical and physical properties of SO, its indications and complications, including particularly emulsification. The mechanisms and risk factors for emulsification are discussed, as well as novel strategies for its effective removal. Finally, the review focuses on new improved formulations of SO, including research into slow‐release pharmacological agents within SO and provides an overview of alternatives to SO for the purpose of long‐term tamponade that are being developed.