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Twists and turns of ocular glymphatic clearance – new study reveals surprising findings in glaucoma
Author(s) -
Rangroo Thrane Vinita,
Hynnekleiv Leif,
Wang Xiaowei,
Thrane Alexander S.,
Krohn Jørgen,
Nedergaard Maiken
Publication year - 2021
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.14524
Subject(s) - glymphatic system , cerebrospinal fluid , interstitial fluid , optic nerve , perivascular space , aquaporin 4 , pathology , medicine , anatomy , lymphatic system , chemistry
its implication in the variations observed in diabetic patients. All these parameters modifying choroidal thickness must be taken into account. As such, one should consider the healthy fellow eye when dealing with a unilateral disease or a healthy patient matched for a wide range of parameters (age, blood pressure, autonomous dysregulation, etc.) for diseases affecting both eyes. In conclusion, current knowledge on CT parameters has not yet given all its clues. It gives hope to better understand its real value and role in the pathophysiology of diabetic retinopathy. Further studies should be done in diabetic patients, which correlate systemic autonomous dysregulation of the cardiovascular system to the modification of CT.