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Ultra‐widefield autofluorescence imaging findings in retinoschisis, rhegmatogenous retinal detachment and combined retinoschisis retinal detachment
Author(s) -
Navaratnam Jesintha,
Salvanos Panagiotis,
Vavvas Demetrios G.,
Bragadóttir Ragnheiður
Publication year - 2021
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.14521
Subject(s) - retinal detachment , ophthalmology , medicine , retinoschisis , fundus (uterus) , retinal
Purpose Retinoschisis (RS), rhegmatogenous retinal detachment (RRD) and combined RS retinal detachment (RSRD) may resemble clinically and pose a diagnostic challenge. This study investigates the role of the fundus autofluorescence (AF) in differentiating RS, RRD and RSRD. Methods Fundus AF changes of 34 eyes diagnosed with RRD, 30 eyes with RS and 12 eyes with RSRD were retrospectively analysed. Ultra‐widefield AF (UW‐AF) image intensities obtained with the Optomap 200Tx were interpreted as hypo‐, hyper‐ and isoautofluorescent or a mixed pattern with hypo‐ and hyperautofluorescence over and at the posterior margin (PM) of RRD, RS and RSRD. Results All RS eyes revealed isoautofluorescence over the area of RS, and nine eyes (30%) showed hypoautofluorescent PM. Among RRD, acute (≤2 weeks) and chronic (>2 weeks) RRD demonstrated distinct AF characteristics. Sixty‐two per cent of RRD eyes had acute RRD. From those, 16 eyes (76%) demonstrated hypoautofluorescence over the detached area and 19 (90%) eyes with hyperautofluorescent PM. Sixty‐two per cent of chronic RRD eyes demonstrated isoautofluorecence over the detached area. Eight RSRD eyes (67%) revealed hyperautofluorescence in the detached area. The positive predictive value (PPV) for hypoautofluorescence over the area of subretinal fluid (SRF) in RRD was 95%. The PPV for hyperautofluorescence over the area of SRF in RSRD was 100% and for isoautofluorescence for schitic area in RSRD and RS was 76%. Conclusion The UW‐AF can be a useful non‐invasive adjuvant tool to distinguish between RRD, RS and RSRD. Hypo‐ or hyperautofluorescence over the area of interest and hyperautofluorescent PM indicates the presence of SRF.