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Correlation between new OCT parameters and metamorphopsia in advanced stages of epiretinal membranes
Author(s) -
Alkabes Micol,
Fogagnolo Paolo,
Vujosevic Stela,
Rossetti Luca,
Casini Giamberto,
De Cillà Stefano
Publication year - 2020
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.14336
Subject(s) - metamorphopsia , optical coherence tomography , epiretinal membrane , ophthalmology , meridian (astronomy) , medicine , foveal , grading (engineering) , retinal , visual acuity , biology , vitrectomy , physics , ecology , astronomy
Purpose To correlate metamorphopsia provided by M‐CHARTS and ectopic inner foveal layers (EIFL) or ‘central bouquet’ abnormality (CBA) in patients with advanced stages of epiretinal membrane (ERM) following the novel Optical Coherence Tomography (OCT)‐based grading scheme. Methods In 60 eyes of 57 patients affected by ERM (stages 3 and 4), the degree of metamorphopsia using the M‐CHARTS was evaluated (M‐SCORE) and correlated with EIFL, CBA and central foveal thickness (CFT) as measured on OCT scans. Results A total of 37 and 23 eyes were diagnosed having ERM stages 3 and 4, respectively. Mean vertical and horizontal M‐SCORE (M‐V and M‐H) were 0.64 ± 0.43 and 0.58 ± 0.37 standard deviations, respectively. Mean M‐SCORE exhibited a statistically significant correlation with EIFL and CFT (both p < 0.0001), but not with CBA (p = 0.84). Analysing the direction of metamorphopsia separately, M‐H and M‐V were significantly correlated with EIFL (both p < 0.0001), but not with CBA thickness (p = 0.70 and 0.33 respectively). Ectopic inner foveal layers (EIFL) was significantly influenced by the presence of CBA (CBA present, 158.29 ± 63.53 micron; CBA absent, 107.05 ± 94.13 micron, p = 0.04). No significant differences were found for both M‐V and M‐H with respect to the presence of CBA. Conclusions Based on the novel OCT‐based grading scheme for ERMs, our results demonstrate that EIFL, but not CBA, might be considered a good indicator for metamorphopsia in patients with advanced ERMs.