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Macular vascular circulation and retinal oxygen saturation changes for idiopathic macular epiretinal membrane after vitrectomy
Author(s) -
Li Zhixi,
Zhang Jie,
Lin Tao,
Peng Wenyan,
Lu Lin,
Hu Jie
Publication year - 2019
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.14066
Subject(s) - retinal , vitrectomy , epiretinal membrane , ophthalmology , medicine , oxygen saturation , visual acuity , oxygen , chemistry , organic chemistry
Abstract Purpose To investigate the postoperative changes in retinal‐choroidal blood flow area and retinal vascular oxygen saturation among patients with idiopathic macular epiretinal membranes ( iERM s). Methods This study prospectively included 24 eyes of 24 consecutive patients who underwent vitrectomy for iERM s. The flow area of choriocapillary layer, retinal superficial capillary plexuses ( SCP s) and retinal deep capillary plexuses ( DCP s) were performed using optical coherence tomography angiography with angiovue prototype software, and retinal vascular oxygen saturation was measured using retinal oximeter with the built‐in software. The flow area of choriocapillary layers and mean retinal vessel oxygen saturation before and after surgery were compared. Results Three months after vitrectomy, the foveal flow area of choriocapillary layer increased clinically significantly from 1.5 ± 0.2 to 1.6 ± 0.2 mm 2 (p = 0.02). The retinal vascular changes of SCP s and DCP s were not statistically significant. The mean retinal arterial oxygen saturation was 89.9 ± 11.3% preoperatively and increased to 94.5 ± 9.7% postoperatively (p = 0.04). Foveal retinal thickness revealed a clinically significant decrease from 547.8 ± 88.2 μ m to 403.0 ± 47.5 μ m after surgery (p < 0.05). Postoperative best corrected visual acuity had no statistically significant correlation with foveal flow area of the choriocapillary layer and retinal vascular oxygen saturation. Conclusions There was a decrease of retinal thickness, an improved flow area of choriocapillary layer in macular region, and an increase of retinal arterial vascular oxygen among iERM s patients after vitrectomy.