All‐in one automated measurement of ocular surface parameters: interferometry, tear meniscus, non‐invasive break‐up time and meibography

analyzed at baseline and 6 months later. At baseline, all the patients performed two consecutive OCT-A acquisitions for reproducibility analysis. Wilcoxon signed-rank test was used to compare the average of consecutive acquisitions. A level of significance a=0.05 was considered. Results: Inclusion of 60 patients at baseline (28 in group 1 and 32 in group 2) and 40 patients at the 6-month follow up (18 patients from group 1 and 22 patients from group 2). Automatic surface area delineation was not different on consecutive acquisitions (p = 0.23). At the 6-month follow-up visit, surface area and FD were lower in group 1 (p < 0.01) and not statistically different in group 2. LAC, density and aspect-ratio were not statistically different. Conclusions: OCT-A can be used to perform quantitative analyses of CNV lesions. Short-term follow up of active and remission CNV reveal blood flow area and fractal dimension modifications related to different vessel maturation status. OCT-A may provide biomarkers of neovascular activity useful for nAMD follow-up.