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All‐in one automated measurement of ocular surface parameters: interferometry, tear meniscus, non‐invasive break‐up time and meibography
Author(s) -
E. Courrier,
V. Lambert,
C. Maurin,
T. Bourlet,
P. Verhoeven,
S.,
Charaoui,
S. Al Bourgol,
E. Crouzet,
C. Perrache,
P. Herbepin,
Z.,
He,
P. Gain,
G. Thuret,
M. C. Trone,
D. Renault,
S. Lazreg,
F. Castignoles,
C. Dommanget,
F. Forest
Publication year - 2018
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13972_83
Subject(s) - meniscus , ophthalmology , interferometry , optometry , medicine , optics , physics , incidence (geometry)
analyzed at baseline and 6 months later. At baseline, all the patients performed two consecutive OCT-A acquisitions for reproducibility analysis. Wilcoxon signed-rank test was used to compare the average of consecutive acquisitions. A level of significance a=0.05 was considered. Results: Inclusion of 60 patients at baseline (28 in group 1 and 32 in group 2) and 40 patients at the 6-month follow up (18 patients from group 1 and 22 patients from group 2). Automatic surface area delineation was not different on consecutive acquisitions (p = 0.23). At the 6-month follow-up visit, surface area and FD were lower in group 1 (p < 0.01) and not statistically different in group 2. LAC, density and aspect-ratio were not statistically different. Conclusions: OCT-A can be used to perform quantitative analyses of CNV lesions. Short-term follow up of active and remission CNV reveal blood flow area and fractal dimension modifications related to different vessel maturation status. OCT-A may provide biomarkers of neovascular activity useful for nAMD follow-up.