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Presenting characteristics and prevalence of polypoidal choroidal vasculopathy in Scandinavian patients with treatment‐naïve exudative age‐related macular degeneration
Author(s) -
Lorentzen Thomas Dam,
Subhi Yousif,
Sørensen Torben Lykke
Publication year - 2018
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13646
Subject(s) - medicine , macular degeneration , ophthalmology , fundus (uterus) , fluorescein angiography , lesion , visual acuity , choroidal neovascularization , surgery
Purpose To study presenting characteristics and prevalence of polypoidal choroidal vasculopathy ( PCV ) in Scandinavian Caucasians with treatment‐naïve exudative age‐related macular degeneration ( AMD ). Methods We reviewed all patients referred in year 2014 and diagnosed using fundus examination, optical coherence tomography, and fluorescein and indocyanine green angiography (ICGA). Details of found PCV s and its subtypes (clinical and angiographical) were correlated to the baseline best‐corrected visual acuity ( BCVA ). Results Of 299 Caucasian patients with a tentative diagnosis of exudative AMD , 18 eyes of 17 patients (5.7%, CI 95%: 3.5–9.1%) had PCV . Patients with PCV were 75.8 ( SD : 7.5) years old and 11 (65%) were females. Lesions were predominantly extramacular. Most eyes (56%) had subretinal haemorrhage, 39% had the exudative type and one (6%) eye had the quiescent type. Larger lesion area and disruption of the foveal inner‐segment/outer‐segment layer correlated with worse baseline BCVA . Polypoidal choroidal vasculopathy ( PCV ) type 1 was present in 50% and PCV type 2 in the other 50%. Polypoidal choroidal vasculopathy ( PCV ) type 1 was associated with a worse baseline BCVA and greater lesion size. Conclusion Polypoidal choroidal vasculopathy ( PCV ) is not a rare condition in Danes with exudative AMD and presents often extramacular and with haemorrhage. This study underscores the importance of ICGA as a part of the diagnostic repertoire in AMD and suggests its routine use in Scandinavian populations.