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Age‐related change and sex difference over 60s in disc‐fovea angle in Japanese population: the Nagahama Study
Author(s) -
Miyata Manabu,
Yoshikawa Munemitsu,
Ohtsuki Hiroshi,
Muraoka Yuki,
Hata Masayuki,
Yokota Satoshi,
Fujimoto Masahiro,
Miyake Masahiro,
Tabara Yasuharu,
Matsuda Fumihiko,
Yoshimura Nagahisa
Publication year - 2018
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13642
Subject(s) - fundus (uterus) , medicine , cohort , age groups , population , ophthalmology , demography , environmental health , sociology
Purpose To analyse the disc‐fovea angle ( DFA ) by age group and to compare sex differences in each age group in a large cohort population. Methods This community‐based cross‐sectional cohort study included 9682 eyes of 9682 volunteers (aged 30–75 years). We measured the DFA , which is the angle between a horizontal line and a line connecting the fovea with the centroid of an optic disc on fundus photographs of the right eye. We manually marked the fovea and surrounded the optic disc. The centroid of an optic disc and the DFA was automatically calculated using originally developed software. We compared the DFA between age groups in 10‐year increments and investigated sex differences of DFA in each age group. Results Overall mean DFA was 6.32 ± 3.53°. The DFA of older subjects was significantly larger than that of younger subjects (p < 0.001). The DFA of women was larger than that of men in their 60s and 70s (p < 0.001 for both), but not in subjects in their 30s, 40s and 50s. Conclusion Larger DFA in women than in men in their 60s and 70s suggests the possibility that age‐related excyclo‐shift occurs more easily in postmenopausal women compared to men of the same age.