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Exophiala phaeomuriformis keratitis in a subarctic climate region: a case report
Author(s) -
Vicente André,
Pedrosa Domellöf Fátima,
Byström Berit
Publication year - 2018
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13624
Subject(s) - medicine , keratitis , dermatology , natamycin , antibiotics , contact lens , amphotericin b , fluconazole , ophthalmology , antifungal , pathology , microbiology and biotechnology , biology
Purpose To report a case of Exophiala phaeomuriformis mycotic keratitis in a patient from a subarctic climate region. Dematiaceous fungi (black yeasts) have been gaining importance as corneal keratitis and ulcer causative agents in certain regions, but no cases have been described in Scandinavia. Methods Case report of a patient with a persistent corneal erosion that eventually presented a brown‐pigmented infiltrate. The patient had a history of several months of topical therapy comprising medication for glaucoma, corticosteroids and antibiotics. A therapeutic contact lens was used, and amniotic membrane transplantation was performed before the development of the pigmented infiltrate. Results Exophiala phaeomuriformis was identified on the microbiological cultures from the surgically obtained infiltrate scrapes. The patient responded to topical amphotericin and fluconazole, the erosion was cured and a stromal scar subsided. During follow‐up, sequential slit‐lamp images and anterior segment optical coherence tomography (OCT) scans were obtained. Conclusion This is the first described case of keratitis caused by E. phaeomuriformis in a subarctic region, the first in Europe and, to our knowledge, the second reported case in the literature. It is important to remember that superficial corneal brown‐pigmented infiltrates should raise the suspicion of an unusual fungal infection even in this climate. This is particularly important in patients with ocular surface disease treated with steroids and antibiotics for a long time.

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