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Long‐term evolution of superficial optic disc drusen
Author(s) -
Malmqvist Lasse,
LundAndersen Henrik,
Hamann Steffen
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13315
Subject(s) - drusen , medicine , visual field , optic nerve , ophthalmology , optic disc , anatomy , population , hyaline , glaucoma , pathology , macular degeneration , environmental health
Purpose Optic disc drusen ( ODD ) is hyaline deposits in the optic nerve head seen in 1–2% of the population. Long‐term evolution of ODD anatomy and visual field defects in ODD patients is a key factor for learning more about pathophysiology and prognosis of the condition. With a median follow‐up period of 56 years, this is the first study that evaluates superficial optic disc anatomy and visual fields in patients with ODD over a life span. Methods Observational case series investigating progression of superficial optic disc anatomy and visual fields in ODD patients. Eight patients with hereditary ODD were included. Results Mean age at initial and follow‐up examination was, respectively, 16.8 and 73.3 years. The median follow‐up time was 56 years. A minimal or non‐existing change in superficial ODD anatomy (size and number) was seen in 10 of 12 eyes. There was a tendency towards more anatomical change in subjects younger at first examination. A 27% decrease in Goldmann perimetric visual field area (cm 2 ) was found between initial and follow‐up examinations. Conclusion Minimal or no change in superficial optic disc anatomy and visual fields in ODD patients oldest at the initial examination suggests that anatomical progression of ODD in patients with hereditary ODD happens primarily before adulthood.