Premium
Ophthalmological findings in children with encephalitis
Author(s) -
Hellgren Kerstin,
Fowler Åsa,
Rydberg Agneta,
Wickström Ronny
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13305
Subject(s) - medicine , encephalitis , pediatrics , interquartile range , ptosis , etiology , sixth nerve palsy , surgery , diplopia , pathology , virus , virology
Purpose To evaluate ophthalmological abnormalities in children with acute encephalitis. Methods Thirty‐six children included in a hospital‐based prospectively and consecutively collected cohort of children with acute encephalitis were investigated for ophthalmological abnormalities. The investigation included clinical ophthalmological examination, fundus photography, neuro‐ophthalmological examinations as well as visual and stereo acuity. Results on laboratory examinations, clinical findings, neuroimaging and electroencephalography registrations were recorded for all children. Results The median age was 4.0 years (Interquartile Range 1.9–9.8). The aetiology was identified in 74% of cases. Three of 36 patients were found to have abnormal ophthalmological findings related to the encephalitis. Transient sixth nerve palsy was seen in a 15‐year‐old child and transient visual impairment was seen in a 3.5‐year‐old child. Bilateral miosis and ptosis, i.e. autonomic nerve system symptoms, were seen in an 11‐month‐old child, with herpes simplex 1 and N ‐methyl‐ d ‐aspartate receptor antibody encephalitis. All three children recovered and improved their ophthalmological function with time. Conclusion Only 3 of 36 children were found to have ophthalmological abnormalities due to encephalitis and they all improved with time. Thus, ophthalmological consultation does not seem to fit in a screening programme for childhood encephalitis but should be considered in selected cases.