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Pachychoroid neovasculopathy: aspect on optical coherence tomography angiography
Author(s) -
Azar Georges,
Wolff Benjamin,
MaugetFaÿsse Martine,
Rispoli Marco,
Savastano MariaCristina,
Lumbroso Bruno
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13221
Subject(s) - optical coherence tomography angiography , optical coherence tomography , medicine , coherence (philosophical gambling strategy) , angiography , ophthalmology , radiology , physics , quantum mechanics
Purpose To describe and interpret the features of pachychoroid neovasculopathy ( PNV ) using optical coherence tomography angiography ( OCTA ) technique. Methods This is an observational case series of patients who presented with PNV . Best‐corrected visual acuity ( BCVA ), anterior segment examination, dilated funduscopic examination, infrared and autofluorescence fundus images and spectral‐domain optical coherence tomography ( SD ‐ OCT ; B‐scan, ‘en‐face’ and OCTA ) were carried out for all patients. Choroid thickness was measured using enhanced depth imaging ( EDI ) mode. Colour fundus photographs, fundus fluorescein angiography ( FFA ) and indocyanine green angiography ( ICGA ) were not performed systematically. Optical coherence tomography angiography (OCTA) features of PNV are described and interpreted. Results Five eyes of five patients with a mean age of 62.2 years (range, 53–73 years) presenting with PNV were analysed. They all presented pachychoroid pigment epitheliopathy ( PPE ) with choroidal thickening and dilated choroidal vessels as seen with EDI ‐ OCT . Fluorescein angiography (FFA) was performed in three patients showing multiple areas of retinal pigment epithelium atrophy and fundus lesions suggestive of chronic central serous chorioretinopathy. Indocyanine green angiography (ICGA) in one patient confirmed the presence of large choroidal veins and choroidal hyperpermeability seen beneath the area of the neovascular tissue. Two eyes had the appearance of polypoidal structures within the neovascular tissue, with the characteristic aspect of the polypoidal lesions on B‐scan and ‘en‐face’. Optical coherence tomography angiography (OCTA) showed the appearance of tangled filamentous vascular network in all eyes. Conclusion Optical coherence tomography angiography (OCTA) is a safe, highly sensitive and specific examination for the detection of type 1 neovascularization associated with PPE . Features are characteristic of tangled filamentous vessels overlying a focal area of thickened choroid.