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Malignant pleural mesothelioma with lacrimal gland metastasis
Author(s) -
Hanafi Hanida,
Verdijk Rob M.,
Paridaens Dion
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13163
Subject(s) - medicine , lacrimal gland , mesothelioma , radiation therapy , biopsy , pathology , metastasis , orbit (dynamics) , lung , magnetic resonance imaging , radiology , cancer , engineering , aerospace engineering
Purpose To describe a rare clinical case of biopsy‐proven metastatic mesothelioma of the lacrimal gland which responded well to chemo and radiation therapy. Methods Interventional case report. Results A 55‐year‐old woman with an untreated malignant biopsy‐proven pleural mesothelioma presented with right proptosis, diplopia and hypoglobus. Magnetic resonance imaging showed an aggressive lacrimal gland tumour with bony erosion. A biopsy concluded a diagnosis of metastatic mesothelioma of the lacrimal gland. Her lacrimal and lung tumours showed a marked regression following palliative chemo (carboplatin) and radiation therapy. Conclusions Malignant pleural mesothelioma may metastasize to the orbit, including the lacrimal gland. A combined chemo and radiation therapy may reduce the size of the metastatic and primary tumour.