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What colour are newborns' eyes? Prevalence of iris colour in the Newborn Eye Screening Test ( NEST ) study
Author(s) -
Ludwig Cassie A.,
Callaway Natalia F.,
Fredrick Douglas R.,
Blumenkranz Mark S.,
Moshfeghi Darius M.
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.13006
Subject(s) - medicine , prospective cohort study , cohort , iris (biosensor) , population , pediatrics , cohort study , optometry , demography , surgery , environmental health , computer science , biometrics , sociology , computer security
Abstract Purpose This study aims to assess the birth prevalence of iris colour among newborns in a prospective, healthy, full‐term newborn cohort. Methods The Newborn Eye Screening Test ( NEST ) study is a prospective cohort study conducted at Lucile Packard Children's Hospital at Stanford University School of Medicine. A paediatric vitreoretinal specialist ( DMM ) reviewed images sent to the Byers Eye Institute telemedicine reading centre and recorded eye colour for every infant screened. Variables were graphed to assess for normality, and frequencies per subject were reported for eye colour, sex, ethnicity and race. Results Among 192 subjects screened in the first year of the NEST study with external images of appropriate quality for visualization of the irides, the birth prevalence of iris colour was 63.0% brown, 20.8% blue, 5.7% green/hazel, 9.9% indeterminate and 0.5% partial heterochromia. The study population was derived from a quaternary care children's hospital. We report the birth prevalence of iris colour among full‐term newborns in a diverse prospective cohort. Conclusion The study demonstrates a broad range of iris colour prevalence at birth with a predominance of brown iris coloration. Future studies with the NEST cohort will assess the change in iris colour over time and whether the frequencies of eye colour change as the child ages.