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Effect of selective laser trabeculoplasty on corneal biomechanics
Author(s) -
Pillunat Karin R.,
Spoerl Eberhard,
Terai Naim,
Pillunat Lutz E.
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.12947
Subject(s) - biomechanics , ophthalmology , medicine , glaucoma , optometry , anatomy
Purpose To evaluate the effect of selective laser trabeculoplasty ( SLT ) on ocular biomechanics as measured with the ocular response analyzer ( ORA , AMETEK Inc. and Reichert Inc.). Methods In a prospective case series, 52 eyes of 52 patients (aged 66.6 ± 9.6 years) with insufficient intraocular pressure ( IOP ) control despite maximum tolerated medical therapy underwent SLT (Solo ™ SLT , Ellex Inc.) for further IOP reduction. Goldmann‐correlated IOP ( IOP g), corneal‐compensated IOP ( IOP cc), corneal hysteresis ( CH ) and the corneal resistance factor ( CRF ) were measured with the ORA prior to and at least 4 weeks following SLT . Results IOP g decreased statistically significantly from 18.0 ± 6.4 to 14.8 ± 3.8 mmHg and IOP cc from 20.2 ± 6.5 to 16.7 ± 3.4 mmHg (p < 0.001). CH increased from 8.53 ± 2.03 to 9.12 ± 1.83 mmHg (p = 0.028) and CRF decreased from 9.58 ± 2.18 to 9.1 ± 2.1 mmHg (p = 0.037), which was statistically significant. Correcting the CH and CRF data for the influence of IOP reduction with a covariance analysis, however, resulted in an unchanged CH ( IOP g adjusted: p = 0.318; IOP cc adjusted: p = 0.468) and CRF ( IOP g adjusted: p = 0.320; IOP cc adjusted: p = 0.464) after SLT . Conclusion Selective laser trabeculoplasty does not change corneal biomechanical properties as measured with the ORA in already pretreated patients with glaucoma. The measured increase in CH and decrease in CRF can be solely explained by IOP reduction.