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Retinal vessel oxygen saturation in a healthy young C hinese population
Author(s) -
Yang Wei,
Fu Yue,
Dong Yanmin,
Lin Leilei,
Huang Xia,
Li Yujie,
Lin Xiaofeng,
Gao Qianying
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.12943
Subject(s) - retinal , dioptre , medicine , oxygen saturation , venule , population , saturation (graph theory) , ophthalmology , oxygen , anatomy , microcirculation , chemistry , visual acuity , mathematics , environmental health , organic chemistry , combinatorics
Purpose To measure retinal vessel oxygen saturation in a healthy young C hinese population and to determine the effects of multiple factors (gender, age, dioptre, vessel diameter and ocular perfusion pressure – OPP ) on retinal oxygen saturation. Methods A total of 126 healthy C hinese individuals aged from 19 to 30 were included in this study. A retinal oximeter ( O xymap T 1) was used to measure retinal vessel oxygen saturation by retinal imaging at two different wavelengths. The mean retinal vessel oxygen saturation ( S at_ O 2 ) of arterioles, venules and arteriovenous ( AV ) difference overall and in four separate quadrants were measured. Intra‐ocular pressure, blood pressure, finger pulse oximetry value, vessel diameter and dioptre were also measured. The correlations between OPP and dioptre, OPP and vessel diameter, and dioptre and vessel diameter were analysed. And the effects of multiple factors on the retinal oxygen saturation were analysed. Results The mean oxygen saturation was 93.2 ± 6.3% in the retinal arterioles, 60.4 ± 5.3% in venules and 32.9 ± 6.4% in AV difference. The temporal quadrants had lower measurements of arteriolar and venular oxygen saturation and AV difference compared with nasal quadrants (p < 0.001). The oxygen saturation of the arterioles, venules and AV difference were unaffected by any unique factor. Arteriolar and venular retinal oxygen saturation correlated negatively with the product of dioptre and OPP . Arteriolar retinal oxygen saturation correlated positively with the product of dioptre and vessel diameter. Conclusions This study provided a normal reference of S at_ O 2 in healthy young C hinese individuals. It was a reflection of the normal state of retinal oxygen metabolism affected by several factors.