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Identification of human papillomavirus in pterygium
Author(s) -
HamedAzzam Shirin,
Edison Natalia,
Briscoe Daniel,
Mukari Abed,
Elmalah Irit
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.12729
Subject(s) - pterygium , human papillomavirus , immunohistochemistry , medicine , pathogenesis , retrospective cohort study , dermatology , pathology , ophthalmology
Abstract Purpose The purpose of this study was to evaluate the involvement of human papillomavirus in the pathogenesis of primary and recurrent pterygium in northern Israel. Methods A retrospective study examined 100 randomly chosen pterygium specimens with solar elastosis, from 100 patients who underwent pterygium surgery during 2012–2013 at the Emek Medical Center. All the specimens were analysed for evidence of human papillomavirus infection by immunohistochemistry. Results Human papillomavirus was not detected in any of the 100 pterygia samples by immunohistochemistry. These used samples were taken from 100 patients with mean age of 51.5 years and a primary: recurrent ratio of 8.09:1. Conclusion We conclude from our study that human papillomavirus infection does not appear to be an important pathogenic factor of pterygium in Israel.