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Hemoadsorption cartridge and coronavirus disease 2019 infections: A case report and brief literature review
Author(s) -
Melegari Gabriele,
Bertellini Elisabetta,
Melegari Alessandra,
Trenti Tommaso,
Malaguti Silvio,
Barbieri Alberto
Publication year - 2021
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/aor.13846
Subject(s) - medicine , cytokine storm , renal replacement therapy , cytokine , intensive care medicine , intensive care unit , cytokine release syndrome , mechanical ventilation , disease , covid-19 , immunology , infectious disease (medical specialty)
The cytokine storm has been frequently reported to occur in patients with severe coronavirus disease 2019 (COVID‐19). Data from the literature suggest that elevated levels of inflammatory mediators, such as interleukin (IL)‐6, IL‐8, and tumor necrosis factor, indicate a severe course or the fatality of the disease. Several therapeutic options have been employed to treat critically ill patients, including hemoadsorption of inflammatory mediators. We here present a case of severe acute respiratory syndrome caused by COVID‐19 and acute renal failure. The patient was admitted to our intensive care unit and treated with mechanical ventilation, renal replacement therapy, and hemoadsorption to reduce the cytokine release syndrome, which plays a fundamental role in the clinical presentation of COVID‐19 patients. We also discuss the potential advantages of reducing cytokine plasma levels using a hemoadsorption cartridge.