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Initial Acute Animal Experiment Using a New Miniature Axial Flow Pump in Series With the Natural Heart
Author(s) -
Okamoto Eiji,
Yano Tetsuya,
Shiraishi Yasuyuki,
Miura Hidekazu,
Yambe Tomoyuki,
Mitamura Yoshinori
Publication year - 2015
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1111/aor.12558
Subject(s) - axial flow pump , impeller , blood flow , axial compressor , hemodynamics , aorta , rotational speed , aortic valve , aortic pressure , descending aorta , materials science , artery , flow (mathematics) , circulatory system , biomedical engineering , medicine , mechanics , cardiology , variable displacement pump , physics , reciprocating pump , engineering , mechanical engineering , gas compressor
Abstract We have advocated an axial flow blood pump called “valvo pump” that is implanted at the aortic valve position, and we have developed axial flow blood pumps to realize the concept of the valvo pump. The latest model of the axial flow blood pump mainly consists of a stator, a directly driven impeller, and a hydrodynamic bearing. The axial flow blood pump has a diameter of 33 mm and length of 74 mm, and the length of anatomical occupation is 33 mm. The axial flow blood pump is anastomosed to the aorta with polytetrafluoroethylene (PTFE) cuffs worn on the inflow and outflow ports. Dp‐ Q curves of the axial flow blood pump are flatter than those of ordinary axial flow pumps, and pump outflow of 5 L /min was obtained against a pressure difference of 50 mm H g at a rotational speed of 9000 rpm in vitro. The axial flow blood pump was installed in a goat by anastomosing with the thoracic descending aorta using PTFE cuffs, and it was rotated at a rotational speed of 8000 rpm. Unlike in case of the ventricular assistance in parallel with the natural heart, pulsatilities of aortic pressure and aortic flow were preserved even when the pump was on, and mean aortic flow was increased by 1.5 L/min with increase in mean aortic pressure of 30 mm H g. In conclusion, circulatory assistance in series with the natural heart using the axial flow blood pump was able to improve hemodynamic pulsatility, and it would contribute to improvement of end‐organ circulation.