Open AccessINTRAMUSCULAR 15(S)15 METHYL PGF 2 α IN THE TREATMENT OF MISSED ABORTION
Author(s) -
Banerjee SK,
Das Gupta S,
Dawn CS,
Mehta AC,
Kanthamani CR,
Krishna Usha R,
Raghavan KS
Publication year - 1988
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.1988.67.s145.45
Subject(s) - medicine , abortion , vomiting , premedication , missed abortion , anesthesia , therapeutic abortion , incomplete abortion , obstetrics , intramuscular injection , fetus , pregnancy , gynecology , genetics , misoprostol , biology
Intramuscular 15(S)15 methyl PGF 2 α (Prostin 15M, Upjohn) was used for induction of labour in cases of missed abortion and intra‐uterine fetal death. The patients received premedication to control the gastrointestinal side effects. Prostin 15M was given at a dose of 250 µ g every three hours and escalated whenever required. The trial was interrupted in two out of 83 patients. Altogether 75 patients (92.6%) expelled the fetus with the treatment. The mean induction abortion interval was 14.7 hours. The primigravidae had a longer (18.2 hrs) interval than the multigravidae (13.8 hrs). The mean number of episodes of vomiting was 2.9 and of diarrhoea 3.5 per patient and treatment.