Open AccessMANAGEMENT OF INTRACTABLE POSTPARTUM HEMORRHAGE SECONDARY TO UTERINE ATONY WITH INTRAMUSCULAR 15(S)15 METHYL PGF 2 α
Author(s) -
Ananthasubramaniam L,
Kuntal Rao,
Sivaraman R,
Raghavan KS
Publication year - 1988
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.1988.67.s145.17
Subject(s) - medicine , uterine atony , oxytocin , intramuscular injection , blood loss , anesthesia , atony , surgery , hysterectomy
In a multicentre trial the efficacy of 250 µ g of intramuscular 15(S)15 methyl PGF 2 α (Prostin 15M, Upjohn) was tested in controlling the postpartum hemorrhage following delivery at term. All patients included in this study did not respond to the conventional therapy of intravenous oxytocin infusion and methergin. Forty‐eight patients were included in this analysis. Forty patients responded to therapy. The blood loss following Prostin 15M injection was significantly (p<0.01) reduced from 666 ml to 341 ml. The mean blood replacement was 833 ml.