Open AccessDevelopment of placental abnormalities in location and anatomy
Author(s) -
Jansen Charlotte H. J. R.,
Kastelein Arnoud W.,
Kleinrouweler C. Emily,
Van Leeuwen Elisabeth,
De Jong Kees H.,
Pajkrt Eva,
Van Noorden Cornelis J. F.
Publication year - 2020
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.13834
Subject(s) - medicine , placenta diseases , anatomy , obstetrics , pregnancy , placenta , fetus , genetics , biology
Low‐lying placentas, placenta previa and abnormally invasive placentas are the most frequently occurring placental abnormalities in location and anatomy. These conditions can have serious consequences for mother and fetus mainly due to excessive blood loss before, during or after delivery. The incidence of such abnormalities is increasing, but treatment options and preventive strategies are limited. Therefore, it is crucial to understand the etiology of placental abnormalities in location and anatomy. Placental formation already starts at implantation and therefore disorders during implantation may cause these abnormalities. Understanding of the normal placental structure and development is essential to comprehend the etiology of placental abnormalities in location and anatomy, to diagnose the affected women and to guide future research for treatment and preventive strategies. We reviewed the literature on the structure and development of the normal placenta and the placental development resulting in low‐lying placentas, placenta previa and abnormally invasive placentas.