Open AccessObstetric synthetic oxytocin use and subsequent hyperactivity/inattention problems in Danish children
Author(s) -
Stokholm Lonny,
Juhl Mette,
Lønfeldt Nicole N.,
Mikkelsen Susanne H.,
Obel Carsten,
StrandbergLarsen Katrine
Publication year - 2018
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1111/aogs.13344
Subject(s) - medicine , danish , oxytocin , strengths and difficulties questionnaire , offspring , odds ratio , logistic regression , pregnancy , cohort study , cohort , odds , pediatrics , psychiatry , mental health , biology , philosophy , linguistics , pathology , genetics
The objective was to examine the association between obstetric synthetic oxytocin use and hyperactivity/inattention problems in offspring. Material and methods We identified children born in 2000–2003, enrolled in the Danish National Birth Cohort, with data on the Strengths and Difficulties Questionnaire ( SDQ ) reported by parents at age seven ( n = 33 896) and age 11 ( n = 27 561) and the children themselves around age 11 ( n = 27 251). Information on oxytocin administration was provided in the Medical Birth Register. We estimated mean differences and odds ratios for childhood hyperactivity/inattention problems according to oxytocin exposure. Results Synthetic oxytocin was administered in 26% of the deliveries. We did not find the use of synthetic oxytocin during birth to be associated with childhood hyperactivity/inattention problems, whether analyzed in linear or logistic regression models. Conclusions Our findings do not support any effects of obstetric use of synthetic oxytocin on hyperactivity/inattention problems in children when measured with the SDQ subscale at 7 or 11 years of age.